The mid-sized 5-Series is a technological tour-de-force. A host of electronics, electronic driving aids, exotic materials and construction techniques set the 5-Series apart from the mainstream. Three engines are offered including a fuel-efficient four cylinder turbo (528i), an inline six-cylinder (535i), and a powerful turbocharged V8 (550i). The 5-Series also offers the xDrive all-wheel-drive system. All models are available with a choice of 6-speed manual or eight-speed automatic. The interior is relatively uncluttered given that a large number of functions are located within the iDrive system that dominates the center console. Unlike many of its competitors, the 5-Series emphasizes the "sport" in sport sedan.

The 528i model now includes a turbocharged four cylinder engine. A gasoline/electric hybrid model joins the lineup.