The Mercedes-Benz S-Class is an icon for the Mercedes brand and serves as a benchmark for all other large luxury sedans. The model range is vast ranging from $91,000 on the lower end to over $200,000 on the upper end. The S-Class is a handsomely styled vehicle with a complex combination of smooth and angular surfaces. Interior trim materials include wood, chrome, leather, and aluminum. The S-Class is packed with technology and safety features including a radar-based cruise control, and active infrared night vision system. The PRE-SAFE system activates the passive and active safety systems if it determines a collision is imminent. In this small but visible segment, buyers can also shop the sporty BMW 7-Series, the understated Audi A8, or the utterly reliable Lexus LS 460. With a huge price spread, the S-Class also competes at the top end with vehicles like the Maserati Quattroporte and Bentley Flying Spur.

The S-Class adds a 50-state compliant diesel model. The S63 is now powered by a new 5.5l turbocharged V8.