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| 2022 Mercedes-Benz S-Class | 2021 Mercedes-Benz S-Class | |
| Price Range | $111,100 - $129,100 | $109,800 - $131,450 |
| Engine(s) | 3.0l I6 T HEV, 4.0l V8 T HEV | 3.0l I6 T HEV, 4.0l V8 T HEV |
| Transmission(s) | A9 | A9 |
| Driven Wheels | AWD | AWD |
| Length / Width / Height | 208.2 / 76.9 / 59.2 | 208.2 / 76.9 / 59.2 |
| Curb Weight (lbs.) | 4610 - 4775 | 4610 - 4775 |