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| 2022 Mercedes-Benz E-Class sedan | 2021 Mercedes-Benz E-Class sedan | |
| Price Range | $54,950 - $75,000 | $54,250 - $107,500 |
| Engine(s) | 2.0l I4 T, 3.0l I6 T HEV | 2.0l I4 T, 3.0l I6 T HEV, 4.0l V8 T |
| Transmission(s) | A9 | A9 |
| Driven Wheels | AWD, RWD | AWD, RWD |
| Length / Width / Height | 194.3 / 73.7 / 57 | 194.3 / 73.7 / 57 |
| Curb Weight (lbs.) | 3781 - 4341 | 3781 - 4497 |