When it was introduced in 2003, the Murano was a unique combination of a car platform and SUV utility. As the market for FWD-biased SUV designs has matured, the third-generation Murano is now one of many similar offerings in the segment. The Murano has four doors, and two rows of seats for five passengers. The large hatch area can hold up to 39.6 cubic feet of cargo with the rear seats up. A standard 3.5l V6 engine producing 260-bhp is mated to a standard continuously variable transmission (CVT).

The third generation Murano is about 3 inches longer and 1 inch wider than its predecessor. A 3.5l V6 engine rated at 260-bhp remains the sole powertrain. Both FWD and AWD models are offered.